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The lymphatic drainage of the breasts is especially relevant to oncology because breast cancer is common to the mammary gland, and cancer cells can metastasize break away from a tumour and be dispersed to other parts of the body by means of the lymphatic system. Mammary intercourse , Breast fetishism , and Stimulation of nipples In some cultures, breasts play a role in human sexual activity. The most frequent benign conditions are puerperal mastitis , fibrocystic breast changes and mastalgia. The areola contains modified sweat glands known as Montgomery's glands. For pubescent girls in thelarche the breast-development stage , the female sex hormones principally estrogens in conjunction with growth hormone promote the sprouting, growth, and development of the breasts. High levels of oxytocin trigger the contraction of muscle cells surrounding the alveoli, causing milk to flow along the ducts that connect the alveoli to the nipple. These glands secrete oily fluid that lubricate and protect the nipple during breastfeeding.

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